This product is a mouse antibody targeting human HER3. This antibody shows a competitive binding with the ligand Heregulin (HRG) to HER3.
Figure 1 The levels of p-HER3 was determined by IHC.
Tumor volumes are expressed as Mean ± S.D.
Wang, Q., Zhang, X., Shen, E., Gao, J., Cao, F., Wang, X., ... & Wang, J. (2016). The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer. Cancer Letters , 380 (1), 20-30.
Figure 2 Antitumor effects in three HER2-negative gastric cancer PDXs.
Tumor specimens of PDX 5 were harvested after the end of treatment followed by analysis of lysates for p-AKT, p-ERK and p-S6.
Wang, Q., Zhang, X., Shen, E., Gao, J., Cao, F., Wang, X., ... & Wang, J. (2016). The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer. Cancer Letters , 380 (1), 20-30.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
PABC-556 | Recombinant Llama Anti-ERBB3 Single Domain Antibody (PABC-556) | ELISA, SPR | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L074E | HRGβ2-PE immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-127 | Human Anti-ERBB3 Recombinant Antibody (PABL-127) | ELISA, WB, FuncS | Human IgG |
PABL-128 | Mouse Anti-ERBB3 Recombinant Antibody (PABL-128) | WB, Block, FuncS | Mouse IgG |
HPAB-0081-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0081-FY) | Inhib, FuncS | Humanized IgG1, κ |
HPAB-0120-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0120-FY) | ELISA, WB | Humanized IgG1, κ |
HPAB-0128-FY | Human Anti-ERBB3 Recombinant Antibody (HPAB-0128-FY) | ELISA | Humanized IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-127 | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBL-127) | ELISA, WB, FuncS | Human scFv |
PSBL-128 | Mouse Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBL-128) | WB, Block, FuncS | Mouse scFv |
HPAB-0477-WJ-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (HPAB-0477-WJ-S(P)) | ELISA, Block | Human scFv |
FAMAB-0047JF-S(P) | Human Anti-ERBB3 Recombinant Antibody (clone PM6); scFv Fragment | WB, ELISA, FuncS | Human scFv |
PSBS-0069 | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBS-0069) | ELISA, Block, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0508CL-S(P) | Anti-Human ERBB3 Recombinant Antibody scFv Fragment (1A5) | ELISA, Inhib, FuncS | |
TAB-0509CL-S(P) | Anti-Human ERBB3 Recombinant Antibody scFv Fragment (3D4) | ELISA, Inhib, FuncS | |
TAB-0552CL-S(P) | Mouse Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-0552CL-S(P)) | ELISA, Inhib | Mouse scFv |
TAB-0553CL-S(P) | Mouse Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-0553CL-S(P)) | ELISA, Inhib | Mouse scFv |
TAB-0508CL-F(E) | Anti-Human ERBB3 Recombinant Antibody Fab Fragment (1A5) | ELISA, Inhib, FuncS |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-057CT | Human Anti-ERBB3 Recombinant Antibody (TAB-057CT) | Inhibion, ELISA | Humanized antibody |
TAB-058CT | Human Anti-ERBB3 Recombinant Antibody (TAB-058CT) | ELISA, Inhib, Cty, IHC, WB, FC | Human IgG1, κ |
TAB-059CT | Anti-Human HER3 Recombinant Antibody (LMAb3) | WB, ELISA, Inhibition, FC | Humanized antibody |
TAB-057CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-057CT-F(E)) | Inhibion, ELISA | Humanized Fab |
TAB-058CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-058CT-F(E)) | WB, ELISA, Inhib | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-061CT | Human Anti-ERBB3 Recombinant Antibody (TAB-061CT) | Inhib, ELISA | Chimeric (Rabbit/Human) antibody |
TAB-061CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P)) | Inhib, ELISA | Human scFv |
TAB-061CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E)) | Inhib, ELISA | Chimeric (Rabbit/Human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-065CT | Human Anti-ERBB3 Recombinant Antibody (TAB-065CT) | ELISA, FC | Human IgG1 |
TAB-066CT | Human Anti-ERBB3 Recombinant Antibody (TAB-066CT) | ELISA, Inhibion, FC | Human IgG |
TAB-062CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-062CT-S(P)) | ELISA, Inhib, FC | Human scFv |
TAB-065CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-065CT-S(P)) | ELISA, FC | Human scFv |
TAB-066CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-066CT-S(P)) | ELISA, Inhibion, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-738CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL932) | Neut, IP | Mouse IgG1 |
NEUT-739CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL483) | FC, CyTOF®, ELISA, Neut | Mouse IgG1 |
NEUT-740CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1019) | Neut | Human IgG1, κ |
NEUT-741CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1020) | Neut | Human IgG1, κ |
NEUT-742CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone M908) | Neut | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1179 | Hi-Affi™ Rabbit Anti-ERBB3 Recombinant Antibody (clone DS1179AB) | ICC, IF, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0081-FY-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0081-FY-F(E)) | Inhib | Humanized Fab |
HPAB-0120-FY-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0120-FY-F(E)) | ELISA, WB | Humanized Fab |
HPAB-0128-FY-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0128-FY-F(E)) | ELISA | Human Fab, κ |
HPAB-0171-WJ-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0171-WJ-F(E)) | ELISA | Human Fab |
HPAB-0200-WJ-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 205.10.1); Fab Fragment | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H21 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-422CQ | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Elgemtumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
AFC-TAB-189 | Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | Human IgG1, κ |
AFC-TAB-H22 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-892 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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