Human Anti-IFNG Recombinant Antibody (clone HuXAF); scFv Fragment (CAT#: HPAB-S0069-YC-S(P))
The humanized immunoglobulins were designed containing mouse AF2 CDR regions and human EU variable regions but containing various subsets of the above substitutions. Haf25 is the same as HuZAF except that the antibody lacks substitutions at positions H11 and H38. HuXAF is the same as huZAF except that the former antibody lacks a substitution at position H38. HuXAF also had better neutralizing activity than haf25, indicating that substitutions at H11 alone made an important contribution to neutralizing activity.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10344/26961_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10344/26961_A_8_3.jpg
Figure 2 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
Figure 2 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000111537-IFNG
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized scFv
- Specificity
- Human IFNG
- Species Reactivity
- Human
- Clone
- HuXAF
- Applications
- ELISA, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Inflammatory Bowel Diseases
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Primary Immunodeficiency
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone HuXAF"
See other products for "IFNG"
Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products
Humanized Antibody Products
ScFv Antibody Products
Mouse Antibody Products
Human Antibody Products
Blocking Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
Epitope-Specific Antibody Products
IgG Antibody Products
Fab Antibody Products
ADCC Enhanced Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-090 | Recombinant Anti-human IFNG VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-140CT | Anti-Human IFN-γ Single Domain Antibody (TAB-140CT), Research Grade Biosimilar | ELISA | Single domain antibody |
| TAB-141CT | Anti-Human IFN-γ Single Domain Antibody (TAB-141CT), Research Grade Biosimilar | ELISA | Single domain antibody |
| TAB-142CT | Anti-Human IFN-γ Single Domain Antibody (TAB-142CT), Research Grade Biosimilar | ELISA | Single domain antibody |
| TAB-143CT | Anti-Human IFN-γ Single Domain Antibody (TAB-143CT), Research Grade Biosimilar | ELISA | Single domain antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-S0069-YC-S(P). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
