H-2Ld/Mycobacterium tuberculosis Ag85A (MPVGGQSSF) MHC Pentamer (CAT#: MHC-YF315)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Ag85A-derived peptide of MPVGGQSSF sequence covering 70-78 and H-2Ld molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Specifications
- Allele
- H-2Ld
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Ag85A
- Antigen Species
- Mycobacterium tuberculosis
- Peptide
- MPVGGQSSF
- Range
- 70-78
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM. FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor. It has a preference for C26:0-CoA over C18:1-CoA.
- Alternative Names
- 85A; mpt44
- Gene ID
- 886132
- UniProt ID
- P9WQP3
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MHC Tetramer for Bacteriology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF311 | A*02:01/Mycobacterium bovis 85-A (GLPVEYLQV) MHC Pentamer | FCM | |
| MHC-YF312 | A*02:01/Mycobacterium bovis 85-A (KLIANNTRV) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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