Recombinant Human Anti-TERT Soluble TCR (ILA1α1β1) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2460)
Human TCR (ILA1α1β1) recognizes TERT peptide (ILAAFLHWL) in the context of HLA-A*02:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (ILA1α1β1). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line LHCN-M2
(Immunofluorescent staining of human cell line LHCN-M2 shows localization to nucleoplasm & nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/1782_B1_17_cr596b5f3cb51d0_selected.jpg
(Immunofluorescent staining of human cell line LHCN-M2 shows localization to nucleoplasm & nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/1782_B1_17_cr596b5f3cb51d0_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows no positivity in hepatocytes and bile duct cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_9_4_selected.jpg
(Immunohistochemical staining of human liver shows no positivity in hepatocytes and bile duct cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_9_4_selected.jpg
Figure 3 Kidney
(Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_7_5.jpg
(Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/142147_A_7_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (ASC TERT1, fHDF/TERT166, HBEC3-KT, hTEC/SVTERT24-B, LHCN-M2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164362-TERT/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164362-TERT/subcellular
Specifications
- Host Species
- Human
- Target
- TERT
- Species Reactivity
- Human
- Epitope
- ILAAFLHWL
- MHC
- HLA-A*02:01
- Clone
- ILA1α1β1
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; Telomerase Catalytic Subunit; EC 2.7.7.49; HEST2; TCS1; EST2; TP2
- Gene ID
- 7015
- UniProt ID
- O14746
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962-F(E) | Recombinant Anti-human TERT Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-962-F(E) | Recombinant Human Anti-human TERT Antibody Fab Fragment | WB, IHC, FuncS | Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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