Aβ
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Derivation: Mouse
Species Reactivity: Human
Type: scFv
Application: WB, FC, FuncS
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Derivation: Mouse
Species Reactivity: Human
Type: Fab
Application: IP, Neut, FuncS
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Derivation: Mouse
Species Reactivity: Human
Type: IgG
Application: ELISA, IF, FuncS
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Derivation: Human
Species Reactivity: Human
Type: IgG
Application: WB, IP, FuncS
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Derivation: Human
Species Reactivity: Human
Type: scFv
Application: WB, IP, FuncS
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Derivation: Human
Species Reactivity: Human
Type: Fab
Application: ELISA, WB, IP, FuncS
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Species Reactivity: Human
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Host Species: Mouse
Specificity: Human
Type: Mouse antibody
Glycosylation site: Fc region
Glycoform (ratio): G2F+4 NeuNAc
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Host Species: Mouse
Specificity: Human
Type: Mouse antibody
Glycosylation site: Fc region
Glycoform (ratio): G2F+4 NeuNAc
Compare
Host Species: Mouse
Specificity: Human
Type: Mouse antibody
Glycosylation site: Fc region
Glycoform (ratio): G2F+4 NeuNAc
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Species Reactivity: Human
Type: Mouse IgG
Application: ELISA
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Species Reactivity: Human
Type: Mouse IgG
Application: IB
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Derivation: Mouse hybridoma cell line
Species Reactivity: Human
Type: Mouse Fab
Application: ELISA
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Species Reactivity: Human
Type: Mouse IgG
Application: ELISA, DB, WB, ELISA, FC
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized scFv
Application: ELISA
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Derivation: Mouse hybridoma cell line
Species Reactivity: Human
Type: Mouse IgG
Application: WB, Neut, FuncS, IHC
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized scFv
Application: ELISA
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Species Reactivity: Human
Type: Mouse Fab
Application: ELISA
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Species Reactivity: Human
Type: Mouse Fab
Application: ELISA
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Species Reactivity: human
Type: scFv-Tat
Application: PCA, WB, FuncS
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Species Reactivity: human
Type: scFv-(+36GFP)
Application: ELISA, Neut, FuncS
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Species Reactivity: human
Type: scFv-(D-Arg)9
Application: ELISA, IF, Neut, FuncS
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized scFv
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized scFv
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA
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Species Reactivity: Human
Type: Mouse scFv
Application: ELISA
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Species Reactivity: Human
Type: Mouse scFv
Application: ELISA
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Species Reactivity: Human
Type: Mouse IgG
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Host Species: Mouse
Specificity: Human
Type: Mouse antibody
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Host Species: Mouse
Specificity: Human
Type: Mouse antibody
Glycosylation site: Fc region
Glycoform (ratio): G2F+4 NeuNAc
Compare
Host Species: Mouse
Specificity: Human
Type: Mouse antibody
Glycosylation site: Fc region
Glycoform (ratio): G2F+4 NeuNAc
Compare
Derivation: Humanized
Species Reactivity: Human
Type: Humanized scFv
Application: ELISA
Compare
Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG
Application: PP, Inhib, ELISA, IF
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG
Application: ELISA
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Host Species: Mouse
Specificity: Human
Type: Mouse antibody
Glycosylation site: Fc region
Glycoform (ratio): G2F+4 NeuNAc
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Derivation: Mouse hybridoma cell line
Species Reactivity: Human
Type: Mouse scFv
Application: ELISA
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