+ Filter
Loading...
Custom Services order now ship next day

Anti-AASS Recombinant Antibody Products

Loading...

Anti-AASS Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Creative Biolabs' Anti-AASS Recombinant Antibodies leverage cutting-edge phage display technology and mammalian expression systems to deliver exceptional specificity and batch-to-batch consistency, empowering researchers to streamline target validation, elucidate enzymatic mechanisms, and accelerate therapeutic development for metabolic disorders.

AASS: A Critical Enzyme in Lysine Catabolism

Creative Biolabs' recombinant antibodies against Alpha-aminoadipic semialdehyde synthase (AASS) are engineered to address the unique challenges of studying this bifunctional enzyme. Our antibodies enable precise detection of AASS isoforms in complex biological samples, supporting applications ranging from immunohistochemistry to functional inhibition assays.

Alternative Names

Aminoadipate-semialdehyde synthase; LKRSDH; LOR; α-AASA synthase; KYAT; NADP-dependent oxidoreductase.

Background

This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Astrocytes, Oligodendrocytes, Hepatocytes, Oligodendrocyte precursor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AN3-CA, NTERA-2, SuSa)

Interaction

Homotetramer.

Molecular function

Multifunctional enzyme, Oxidoreductase

More Types Infomation

Anti-AASS rAb Products

Creative Biolabs provides a meticulously curated collection of anti-AASS antibodies, each one thoroughly validated across multiple species and diverse experimental models. This comprehensive validation process ensures that researchers can rely on consistent and reproducible results, whether their focus is on drug screening, disease modeling, or molecular diagnostic applications.

Cat. No. Product Name Target Species Host Species Applications
MOR-0006 Hi-Affi™ Rabbit Anti-AASS Recombinant Antibody (clone DS6AB) Human Rabbit WB, IHC-P

Table.1 Featured anti-AASS recombinant antibody products at Creative Biolabs.

Creative Quality Control

Every anti-AASS antibody undergoes rigorous validation. Our ISO-certified workflows guarantee >95% purity and lot-to-lot reproducibility, critical for translational research and preclinical studies.

IF analysis. (Creative Biolabs Original)Fig.1 IF staining of anti-AASS antibody.
(Cat# MOR-0006, Creative Biolabs).

IF staining. (Creative Biolabs Original)Fig.2 IF-staining result of anti-AASS antibody.
(Cat# MOR-0006, Creative Biolabs).

IHC analysis. (Creative Biolabs Original)Fig.3 Kidney IHC staining of anti-AASS antibody.
(Cat# MOR-0006, Creative Biolabs).

Liver IHC analysis. (Creative Biolabs Original)Fig.4 Liver IHC staining of anti-AASS antibody.
(Cat# MOR-0006, Creative Biolabs).

Customer Reviews

Excellent
Ja***s**
Rabbit Anti-AASS Recombinant Antibody (clone R01-9D6)
The anti-AASS antibody's superior cross-species reactivity transformed our murine hyperlysinemia model studies.
10/Mar/2024
Excellent
Dr***n**
Hi-Affi™ Rabbit Anti-AASS Recombinant Antibody (clone DS143AB)
Their antibody's functional blocking capacity simplified our enzyme kinetic assays, saving weeks of optimization.
20/Oct/2023

rAb Production

Our serum-free mammalian platform ensures scalable, endotoxin-free antibody production. From gene synthesis to glyco-engineering, we deliver gram-scale quantities with tailored formats to meet diverse research and therapeutic needs.

Featured Anti-AASS Recombinant Antibody Production PlatformsMilligram-scale. (Creative Biolabs Original)
Fig.5 Milligram-scale synthesis of recombinant anti-AASS antibodies.

Gram-scale. (Creative Biolabs Original)Fig.6 Production of recombinant anti-AASS antibodies at the gram scale.

rAb Modalities

Choose from fragment antigen-binding (Fab), single-domain VHH, or bispecific formats optimized for in vivo imaging, flow cytometry, or therapeutic candidate screening. Our modular engineering supports seamless integration into your existing workflows.

AASS antibody production and modalities. (Creative Biolabs Original)Fig.7 Methods and modalities for the production of full-length recombinant anti-AASS antibodies.

Creative Biolabs combines decades of antibody engineering excellence with a client-centric approach. Whether you require off-the-shelf reagents or bespoke solutions, our team is equipped to advance your AASS-related projects. With decades of experience in antibody engineering, Creative Biolabs merges its technical expertise with a keen focus on client needs, ensuring tailored support for each unique project. Whether your research demands readily available reagents or customized solutions, our dedicated team stands ready to propel your AASS-related endeavors forward. Contact our experts today to discuss your requirement!

Go to compare

Go to compare

Merry Christmas & Happy New Year
Happy Thanksgiving close ad