ABL1
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene. Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Class: Class I
Antigen: BCR-ABL 210 kD fusion protein
Antigen Species: Human
Peptide: ATGFKQSSK
Conjugate: Unlabeled, Biotin, R-PE, APC
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Class: Class I
Antigen: BCR-ABL
Antigen Species: Human
Peptide: GVRGRVEEI
Conjugate: Unlabeled, Biotin, R-PE, APC
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: HSATGFKQSSK
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: GKQSSKALQR
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: GKQSSKALQR
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: QQAHCLWCV
Conjugate: Unconjugated
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: QQAHCLWCV
Conjugate: FITC
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: QQAHCLWCV
Conjugate: APC
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: QQAHCLWCV
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: CLWCVPQLR
Conjugate: Unconjugated
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: CLWCVPQLR
Conjugate: FITC
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: GFKQSSKALQR
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: GFKQSSKALQR
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: GFKQSSKAL
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: ATGFKQSSKAL
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: ATGFKQSSK
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: ATGFKQSSK
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: CLWCVPQLR
Conjugate: APC
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: CLWCVPQLR
Conjugate: PE
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Class: Class II
Antigen: ABL1
Antigen Species: Human
Peptide: KQSSKALQRPVA
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: SATGFKQSSK
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: LTINKEEAL
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: KQSSKALQR
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: KQSSKALQR
Conjugate: PE
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Class: Class I
Antigen: ABL1
Antigen Species: Human
Peptide: HSATGFKQSSK
Conjugate: PE
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Class: Class I
Antigen: BCR-ABL
Antigen Species: Human
Peptide: GVRGRVEEI
Conjugate: BV421
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Class: Class I
Antigen: BCR-ABL
Antigen Species: Human
Peptide: GVRGRVEEI
Conjugate: APC
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Class: Class I
Antigen: BCR-ABL
Antigen Species: Human
Peptide: GVRGRVEEI
Conjugate: PE
Compare
Class: Class I
Antigen: BCR-ABL 210 kD fusion protein
Antigen Species: Human
Peptide: KQSSKALQR
Conjugate: Unlabeled, Biotin, R-PE, APC
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Species Reactivity: Human
Type: Mouse IgG1
Application: IHC-P
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Scaffold Name: 10-FnIII
Target: Abelson (Abl) kinase SH2 domain
Species Reactivity: Human
Derivation: Phage display
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Species Reactivity: Human
Type: Mouse IgG
Application: WB, ELISA
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Species Reactivity: Human
Type: Llama VHH
Application: WB, ICC, ChiP, FA, ELISA
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Scaffold Name: Src homology domain 3 (SH3)
Target: APTYPPPLPP (Abl-pep)
Species Reactivity: Human
Derivation: Phage display
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Scaffold Name: SH3 domain
Target: SH3 domain of the Abelson tyrosine kinase (Abl-SH3).
Species Reactivity: Human
Derivation: Phage display
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Species Reactivity: Human
Type: Mouse IgG1
Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.