Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Transporters
Intracellular, Membrane (different isoforms)
Group enriched (Plasma cells, monocytes, B-cells, T-cells)
Low immune cell specificity
Cell line enhanced (Daudi, Karpas-707, RPMI-8226, SK-BR-3, U-266/70, U-266/84, U-698)
Interacts (via cytoplasmic C-terminal domain) with USP4; the interaction is direct (PubMed:16339847). May interact with DRD4 (PubMed:18832607). Interacts with NECAB2 (PubMed:17689978). Interacts (via cytoplasmic C-terminal domain) with GAS2L2; interaction enhances receptor-mediated adenylyl cyclase activity (By similarity).
G-protein coupled receptor, Receptor, Transducer
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For Research Use Only. Not For Clinical Use.