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AK5

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Early spermatids)

Immune cell specificity

Immune cell enhanced (naive CD4 T-cell, myeloid DC)

Cell line specificity

Cell line enhanced (ASC TERT1, BJ, fHDF/TERT166, LHCN-M2, U-2 OS)

Interaction

Monomer. Interacts with YWHAZ (PubMed:16959763).

Molecular function

Kinase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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