C1s
The complement system is a well-known effector mechanism of the immune response, providing not only protection against pathogens and other harmful agents but also recovery from injury. The complement pathway comprises a number of proteins that typically exist in the body in an inactive form. The classical complement pathway is triggered by activation of the first component of complement, referred to as the CI complex, which consists of Clq, Clr, and Cls proteins. Upon binding of CI to an immune complex or other activator, the Cls component, a diisopropyl fluorophosphate (DFP)-sensitive serine protease, cleaves complement components C4 and C2 to initiate activation of the classical complement pathway. The classical complement pathway appears to play a role in many diseases and disorders.
Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG2a
Application: WB, IP, IHC, FuncS
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Derivation: Phage display library screening
Species Reactivity: Human
Type: Rabbit IgG
Application: ELISA
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Derivation: Phage display library screening
Species Reactivity: Human
Type: Rabbit IgG
Application: WB
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Species Reactivity: Human
Type: Mouse IgG2a
Application: ELISA
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Species Reactivity: Human
Type: Mouse IgG2a
Application: WB, Neut, FC, IA, IHC, IHC-Fr, IHC-P
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Species Reactivity: Human
Type: Mouse IgG1
Application: FC, FuncS, IA, IP, WB
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Derivation: Humanized (mouse/human)
Species Reactivity: Human, Cynomolgus monkey
Type: Humanized IgG
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA
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Derivation: Humanized (mouse/human)
Species Reactivity: Human, Cynomolgus monkey
Type: Humanized scFv
Application: ELISA
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Derivation: Humanized (mouse/human)
Species Reactivity: Human, Cynomolgus monkey
Type: Humanized Fab
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG
Application: ELISA
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Derivation: Humanized
Species Reactivity: Human
Type: Human scFv
Application: ELISA
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Species Reactivity: Human
Type: Humanized Fab
Application: ELISA, Stim, Inhib
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Species Reactivity: Cross-reacts with C1s from at least two monkey species
Type: Mouse Fab
Application: ELISA, Stim, Inhib
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Application: ELISA, FuncS
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Application: ELISA, FuncS
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Application: ELISA, FuncS
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Application: ELISA, FuncS
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Species Reactivity: Human
Type: Llama VHH
Application: WB, ICC, ChiP, FA, ELISA
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Species Reactivity: Human
Type: Humanized scFv
Application: ELISA, Stim, Inhib
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Species Reactivity: Cross-reacts with C1s from at least two monkey species
Type: Mouse scFv
Application: ELISA, Stim, Inhib
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Species Reactivity: Human
Type: Humanized Antibody
Application: ELISA, CMDC, Stim, Hemolysis, Inhib
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Species Reactivity: Cross-reacts with C1s from at least two monkey species
Type: Mouse IgG
Application: ELISA, CMDC, Stim, Hemolysis, Inhib
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For Research Use Only. Not For Clinical Use.