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C76H142O15

scTCR
Mycolates comprise a structurally diverse species of Mtb cell wall lipids that can activate CD1b-restricted human T cells, including GEM T cells. TCRαβ+ CD1b-restricted mycolate-specific GEM lymphocytes are a conserved T cell population in humans that expands upon Mtb infection and exhibits potent antimycobacterial effector functions through production of IFN-γ and TNF-α.

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