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CD300A

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For Research Use Only. Not For Clinical Use.


CD300A (CD300a Molecule) is a Protein Coding gene. Diseases associated with CD300A include Kabuki Syndrome 1. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include phosphatidylserine binding and signaling receptor activity. An important paralog of this gene is CD300C.
Protein class

CD markers, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (NK-cells, Hofbauer cells, dendritic cells, Kupffer cells, Macrophages, granulocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Group enriched (HMC-1, NB-4, RPMI-8226)

Interaction

Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.

Molecular function

Receptor

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