CD markers, FDA approved drug targets
Intracellular, Membrane (different isoforms)
Cell type enhanced (monocytes, Macrophages, Langerhans cells, Hofbauer cells, Kupffer cells, Microglial cells)
Group enriched (non-classical monocyte, classical monocyte, intermediate monocyte, myeloid DC, memory B-cell, naive B-cell)
Cell line enriched (HDLM-2)
Homodimer. Interacts with MARCH8. Interacts (via cytoplasmic domain) with PHB1 and PHB2; the interactions increases after priming with CD40 (By similarity). (Microbial infection) Interacts with adenovirus subgroup b fiber protein.
Host cell receptor for virus entry, Receptor
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For Research Use Only. Not For Clinical Use.