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CX3CR1
CX3CR1 (C-X3-C Motif Chemokine Receptor 1) is a Protein Coding gene. Diseases associated with CX3CR1 include Macular Degeneration, Age-Related, 12 and Human Immunodeficiency Virus Type 1. Among its related pathways are Akt Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR4.
Protein class
Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets
Predicted location
Membrane
Single cell type specificity
Group enriched (NK-cells, Microglial cells)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Cell line enriched (RPMI-8226)
Interaction
Found in a ternary complex with CX3CL1 and ITGAV:ITGB3 or ITGA4:ITGB1. (Microbial infection) Interacts with human respiratory syncytial virus (HRSV) protein G; this interaction modulates host immune response. (Microbial infection) Interacts with HIV-1 envelope polyprotein gp160.
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
- Chicken Anti-CX3CR1 Polyclonal IgY (BRD-0146MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: indirect ELISA, WB
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- Chicken Anti-CX3CR1 Polyclonal IgY (BRD-0988MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: ELISA, WB
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- Mouse Anti-CX3CR1 Recombinant Antibody (VS3-FY2681) (VS3-FY2681)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ICC, FC, ELISA
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- Llama Anti-CX3CR1 Recombinant Antibody (HPAB-0624-CN) (HPAB-0624-CN)
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- Derivation: VHH phage display library
- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, BL
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- Llama Anti-CX3CR1 Recombinant Antibody (HPAB-0623-CN) (HPAB-0623-CN)
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- Derivation: VHH phage display library
- Species Reactivity: Human, Cynomolgus monkey
- Type: Llama VHH
- Application: ELISA, FC, BL
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- Llama Anti-CX3CR1 Recombinant Antibody (HPAB-0622-CN) (HPAB-0622-CN)
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- Derivation: VHH phage display library
- Species Reactivity: Human, Cynomolgus monkey
- Type: Llama VHH
- Application: ELISA, FC, BL
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- Mouse Anti-Mouse Cx3cr1 Recombinant Antibody (clone QA16A03) (VS-0224-XY83)
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- Species Reactivity: Mouse
- Type: Human IgG1, kappa
- Application: FC
Compare
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For Research Use Only. Not For Clinical Use.