DSG1
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
Derivation: Phage display library
Species Reactivity: Human, Mouse
Type: Human Fab
Application: ELISA, IF, IB
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Derivation: Phage display library
Species Reactivity: Human, Mouse
Type: Human Fab
Application: ELISA, IF, IB
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Species Reactivity: Human, Mouse
Type: Rabbit IgG
Application: WB, IHC
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Derivation: Phage display library
Species Reactivity: Human, Mouse
Type: Human IgG
Application: ELISA, IF, IB
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Derivation: Phage display library
Species Reactivity: Human, Mouse
Type: Human IgG
Application: ELISA, IF, IB
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Derivation: Phage display library
Species Reactivity: Human, Mouse
Type: Human scFv
Application: ELISA, IF, IB
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Derivation: Phage display library
Species Reactivity: Human, Mouse
Type: Human scFv
Application: ELISA, IF, IB
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1, κ
Application: WB, IP, IF, IHC
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Derivation: Phage display library
Species Reactivity: Human
Type: Rabbit IgG
Application: WB
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Species Reactivity: Human
Type: Mouse antibody
Application: ICC/IF, IP WB
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Species Reactivity: Human
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Species Reactivity: Human
Type: Human scFv
Application: ELISA
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Species Reactivity: Cross-react with Dsg4
Type: Human Fab
Application: ELISA, IF, IP
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Species Reactivity: Cross-react with Dsg4
Type: Human IgG
Application: ELISA, IF, IP
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Derivation: Humanized
Species Reactivity: Human
Type: Antibody
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Derivation: Humanized
Species Reactivity: Human
Type: ADCC enhanced antibody
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Species Reactivity: Human
Type: Human Fab
Application: ELISA
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Species Reactivity: Cross-react with Dsg4
Type: Human scFv
Application: ELISA, IF, IP
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Species Reactivity: Human, Mouse, Rat
Type: Rabbit IgG
Application: WB, IHC-P, ICC, IF
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Species Reactivity: Human
Type: Human IgG
Application: ELISA, Inhib
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For Research Use Only. Not For Clinical Use.