F11R
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, IP, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, IF, IP, FuncS
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC, IHC, ICC, Neut
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, FuncS, IF, IP, WB
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- Species Reactivity: Mouse
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Activ
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Activ
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Mouse IgG
- Application: Activ
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: WB, IP, IF
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, WB, IF
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- Species Reactivity: Mouse
- Type: Rat Fab
- Application: WB, IP, IF
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG4, κ
- Application: In vivo activity
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG4, κ
- Application: ELISA, WB, IF
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ICC, FC, WB, FUNC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: In vivo activity
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, WB, IF
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human Fab, κ
- Application: In vivo activity
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG4, κ
- Application: ELISA, WB, IF
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB, IF
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- Application: IF, IHC, FC, WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.