GHR
This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, FC
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB, Neut
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, Neut
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, Neut
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Rat
- Type: Mouse antibody
- Application: FC, IHC-Fr, IHC-P, IP
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- Species Reactivity: Rat
- Type: Mouse IgG2a
- Application: WB, Neut
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB, Neut
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- Species Reactivity: Rat
- Type: Rabbit IgG
- Application: WB, IP
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC, IF
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: FA, FC, ICC, ELISA
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- Species Reactivity: Human
- Application: ELISA, FC, IP, WB
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- Species Reactivity: Human
- Application: FC, IP, Inhib
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus monkey
- Application: ELISA, FC
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- Species Reactivity: Human
- Application: ELISA, FC, IP, WB
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus monkey
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Antibody
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus monkey
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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