Enzymes, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (dendritic cells, Macrophages, Theca cells, Hofbauer cells, Adipocytes, Pancreatic endocrine cells, T-cells)
Low immune cell specificity
Cell line enhanced (NB-4, REH)
Interacts with the heterodimer formed by GNB1 and GNG2 (By similarity). Interacts with GIT1 (By similarity). Interacts with, and phosphorylates chemokine-stimulated CCR5 (PubMed:10085131). Interacts with ARRB1 (PubMed:9501202). Interacts with LPAR1 and LPAR2 (PubMed:19306925). Interacts with RALA in response to LPAR1 activation (PubMed:19306925). ADRBK1 and RALA mutually inhibit each other's binding to LPAR1 (PubMed:19306925). Interacts with ADRB2 (PubMed:19715378).
Kinase, Serine/threonine-protein kinase, Transferase
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For Research Use Only. Not For Clinical Use.