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HIGD1A

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For Research Use Only. Not For Clinical Use.


Background

HIGD1A (HIG1 Hypoxia Inducible Domain Family Member 1A) is a Protein Coding gene. Diseases associated with HIGD1A include Hypoxia. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cellular Senescence (REACTOME). An important paralog of this gene is ENSG00000280571.
Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Distal enterocytes, Distal tubular cells, Paneth cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC)

Cell line specificity

Low cell line specificity

Interaction

Associates with cytochrome c oxidase (COX, complex IV); proposed complex component. Also associates with respiratory chain supercomplexes.

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