+ Filter
Loading...
IFNAR2
Loading...Anti-IFNAR2 Products
- Recombinant Anti-human IFNAR2 Antibody (MOB-536)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, Neut, FuncS
Compare
- Recombinant Human Anti-human IFNAR2 Antibody Fab Fragment (MHH-536-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: IP, IF, Biosensors, FuncS
Compare
- Recombinant Human Anti-human IFNAR2 Antibody scFv Fragment (MHH-536-S(P))
-
- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
Compare
- Recombinant Anti-human IFNAR2 Antibody Fab Fragment (MOB-536-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, ELISA, FuncS
Compare
- Recombinant Anti-human IFNAR2 Antibody scFv Fragment (MOB-536-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IF, FuncS
Compare
- Anti-Mouse IFNAR2 Immunohistochemistry Kit (VS-0525-XY3411)
-
- Species Reactivity: Mouse
- Target: IFNAR2
- Application: IHC
Compare
- Chicken Anti-IFNAR2 Polyclonal IgY (BRD-0868MZ)
-
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
Protein class
Cancer-related genes, Disease related genes, FDA approved drug targets
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Plasma cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (Karpas-707, U-266/70, U-266/84)
Interaction
Heterodimer with IFNAR1 (PubMed:8181059, 7665574, 10049744, 24075985, 21854986). Interacts with the transcriptional factors STAT1 and STAT2 (PubMed:9121453, 28165510). Interacts with JAK1 (PubMed:8181059, 7759950). Interacts with USP18; indirectly via STAT2, it negatively regulates the assembly of the ternary interferon-IFNAR1-IFNAR2 complex and therefore type I interferon signaling (PubMed:28165510).
Molecular function
Receptor
More Types Infomation