IL-17A & IL-23
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
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- Targets: IL-17A & IL-23
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
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For Research Use Only. Not For Clinical Use.