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IL17 & TNF

Anti-IL17 & TNF Products

Anti-Human TNF Recombinant Antibody (Infliximab) (TAB-006)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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Anti-Human TNF Recombinant Antibody (TAB-010) (TAB-010)
- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: WB, FC, IP, ELISA, Neut, FuncS, IF
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Anti-Human TNF alpha Recombinant Antibody Fab Fragment (TAB-034-F(E)) (TAB-034-F(E))
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab'
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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Anti-Human IL-17 Recombinant Antibody Fab Fragment (CAT-2200) (TAB-077ZJ-F(E))
- Species Reactivity: Cynomolgus monkey, Canine, Human
- Type: Human antibody
- Application: ELISA, WB, Inhib, Neut
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Human Anti-IL17 Recombinant Antibody; Fab Fragment (TAB-081ZJ-F(E)) (TAB-081ZJ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody Fab Fragment (c632.1) (TAB-082ZJ-F(E))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Human Anti-TNF Recombinant Antibody (TAB-115CQ) (TAB-115CQ)
- Derivation: Humanized
- Species Reactivity: Human, Rhesus macaque, Cynomolgus, Canine
- Type: Humanized antibody
- Application: ELISA, FC, Neut
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Anti-Human IL-17 Recombinant Antibody Fab Fragment (TAB-047ZJ-F(E)) (TAB-047ZJ-F(E))
- Species Reactivity: Cynomolgus monkey, Marmoset monkey, Human
- Type: Humanized antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (CDP571) (TAB-110CQ)
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (B5) (TAB-111CQ)
- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
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Human Anti-TNF Recombinant Antibody (TAB-114CQ) (TAB-114CQ)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, Inhib
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Human Anti-TNF Recombinant Antibody (TAB-397CQ) (TAB-397CQ)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-398CQ) (TAB-398CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-396CQ) (TAB-396CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-399CQ) (TAB-399CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: WB
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Anti-Human TNF Recombinant Antibody (TAB-400CQ) (TAB-400CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-118CQ) (TAB-118CQ)
- Species Reactivity: Human
- Type: Humanized antibody
- Application: FC, ELISA
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Human Anti-TNF Recombinant Antibody (TAB-401CQ) (TAB-401CQ)
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
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Human Anti-TNF Recombinant Antibody (TAB-119CQ) (TAB-119CQ)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, BL
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Human Anti-TNF Recombinant Antibody (TAB-402CQ) (TAB-402CQ)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-120CQ) (TAB-120CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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Anti-Human TNF Recombinant Antibody (TAB-404CQ) (TAB-404CQ)
- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-121CQ) (TAB-121CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-131CQ-F(E)) (TAB-131CQ-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-396CQ-S(P)) (TAB-396CQ-S(P))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (XENP6401) (TAB-405CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody (TAB-122CQ) (TAB-122CQ)
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FuncS
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Anti-Human TNF Recombinant Antibody (TAB-254) (TAB-254)
- Derivation: Human
- Species Reactivity: Human
- Type: [V-kappa]2 - Fc
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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Afuco™ Anti-Human TNF ADCC Recombinant Antibody (AVX-470), ADCC Enhanced (AFC-601CL)
- Derivation: Cow
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Human Anti-TNF Recombinant Antibody (clone A2) (PABL-349)
- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
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Mouse Anti-TNF Recombinant Antibody (clone 18C3) (MOB-1076z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, FuncS
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Anti-Human IL-17 Recombinant Antibody (TAB-047ZJ) (TAB-047ZJ)
- Species Reactivity: Cynomolgus monkey, Marmoset monkey, Human
- Type: Humanized antibody
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody (CAT-2200) (TAB-077ZJ)
- Species Reactivity: Cynomolgus monkey, Canine, Human
- Type: Human antibody
- Application: ELISA, WB, Inhib, Neut
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Human Anti-IL17 Recombinant Antibody (TAB-081ZJ) (TAB-081ZJ)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody (c632.1) (TAB-082ZJ)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody scFv Fragment (TAB-047ZJ-S(P)) (TAB-047ZJ-S(P))
- Species Reactivity: Cynomolgus monkey, Marmoset monkey, Human
- Type: Humanized antibody
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody scFv Fragment (CAT-2200) (TAB-077ZJ-S(P))
- Species Reactivity: Cynomolgus monkey, Canine, Human
- Type: Human antibody
- Application: ELISA, WB, Inhib, Neut
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Human Anti-IL17 Recombinant Antibody; scFv Fragment (TAB-081ZJ-S(P)) (TAB-081ZJ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody scFv Fragment (c632.1) (TAB-082ZJ-S(P))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; scFv Fragment (TAB-397CQ-S(P)) (TAB-397CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Anti-Human TNF Recombinant Antibody Fab Fragment (2SD4) (TAB-133CQ-F(E))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
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Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-396CQ-F(E)) (TAB-396CQ-F(E))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody Fab Fragment (AE11-5) (TAB-135CQ-F(E))
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human antibody
- Application: ELISA, Neut
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Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-397CQ-F(E)) (TAB-397CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-399CQ-S(P)) (TAB-399CQ-S(P))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-137CQ-F(E)) (TAB-137CQ-F(E))
- Species Reactivity: Human, Cynomolgous macaque
- Type: Human Fab
- Application: ELISA, FC, IF
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Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-400CQ-F(E)) (TAB-400CQ-F(E))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; scFv Fragment (TAB-113CQ-S(P)) (TAB-113CQ-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; scFv Fragment (TAB-114CQ-S(P)) (TAB-114CQ-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, Neut
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Human Anti-TNF Recombinant Antibody; scFv Fragment (TAB-401CQ-S(P)) (TAB-401CQ-S(P))
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-138CQ-F(E)) (TAB-138CQ-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IF
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Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) (TAB-402CQ-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-401CQ-F(E)) (TAB-401CQ-F(E))
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-398CQ-F(E)) (TAB-398CQ-F(E))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-136CQ-F(E)) (TAB-136CQ-F(E))
- Species Reactivity: Human, Rabbit
- Type: Human Fab
- Application: ELISA, Block
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Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-400CQ-S(P)) (TAB-400CQ-S(P))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody Fab Fragment (TAB-399CQ-F(E)) (TAB-399CQ-F(E))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody scFv Fragment (CDP571) (TAB-110CQ-S(P))
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody scFv Fragment (B5) (TAB-111CQ-S(P))
- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
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Anti-Human TNF Recombinant Antibody scFv Fragment (TAB-398CQ-S(P)) (TAB-398CQ-S(P))
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
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Anti-Human TNF Recombinant Antibody Fab Fragment (hMAK195) (TAB-134CQ-F(E))
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, Neut
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Anti-Human TNF Single Domain Antibody (TAB-414CQ), Research Grade Biosimilar (TAB-414CQ)
- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut
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Anti-Human TNF Recombinant Antibody scFv Fragment (A10G10) (TAB-112CQ-S(P))
- Species Reactivity: Human
- Application: ELISA, WB
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Rabbit Anti-TNF Recombinant Antibody; Fab Fragment (TAB-139CQ-F(E)) (TAB-139CQ-F(E))
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, FC, IF
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Anti-Human TNF Single Domain Antibody (TAB-415CQ), Research Grade Biosimilar (TAB-415CQ)
- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut, FunS
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Anti-Human TNF Single Domain Antibody (TAB-413CQ), Research Grade Biosimilar (TAB-413CQ)
- Species Reactivity: Human, Rat
- Type: Single domain antibody
- Application: ELISA, WB, Neut
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Rabbit Anti-TNF Recombinant Antibody; Fab Fragment (TAB-271CQ-F(E)) (TAB-271CQ-F(E))
- Species Reactivity: Human
- Type: Rabbit Fab
- Application: ELISA, WB
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Mouse Anti-IL17 Recombinant Antibody; scFv Fragment (TAB-028ZJ-S(P)) (TAB-028ZJ-S(P))
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody scFv Fragment (TAB-029ZJ-S(P)) (TAB-029ZJ-S(P))
- Species Reactivity: Human
- Application: ELISA
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Mouse Anti-IL17 Recombinant Antibody; scFv Fragment (TAB-031ZJ-S(P)) (TAB-031ZJ-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Mouse Anti-IL17 Recombinant Antibody; Fab Fragment (TAB-027ZJ-F(E)) (TAB-027ZJ-F(E))
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Mouse Anti-IL17 Recombinant Antibody; scFv Fragment (TAB-027ZJ-S(P)) (TAB-027ZJ-S(P))
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody (TAB-029ZJ) (TAB-029ZJ)
- Species Reactivity: Human
- Application: ELISA
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Mouse Anti-IL17 Recombinant Antibody (TAB-028ZJ) (TAB-028ZJ)
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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Mouse Anti-IL17 Recombinant Antibody (TAB-027ZJ) (TAB-027ZJ)
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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Recombinant Anti-human TNF VHH Single Domain Antibody (NABL-051)
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, IHC, FC, FuncS
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Human Anti-TNF Recombinant Antibody (clone A2); scFv Fragment (PSBL-349)
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
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Human Anti-TNF Recombinant Antibody (clone A2); Fab Fragment (PFBL-349)
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
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Mouse Anti-IL17 Recombinant Antibody (TAB-031ZJ) (TAB-031ZJ)
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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10-FnIII scaffold protein anti-Human TNFα (SFN-L026)
- Scaffold Name: 10-FnIII
- Target: TNFα
- Species Reactivity: Human
- Derivation: mRNA Display
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Kunitz domains scaffold protein anti-Human TNFα (SKD-L116)
- Scaffold Name: Kunitz domains
- Target: TNFα
- Species Reactivity: Human
- Derivation: Phage display
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Z-domain of protein A scaffold protein anti-Human TNFα (SZA-L241)
- Scaffold Name: Z-domain of protein A
- Target: TNFα
- Species Reactivity: Human
- Derivation: Phage display
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Ubiquitin scaffold protein anti-TNFα (SUB-L209)
- Scaffold Name: Ubiquitin
- Target: TNFα
- Derivation: Phage display
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Anti-TNF alpha Recombinant Antibody (TAB-768) (TAB-768)
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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Bovine Anti-TNF Recombinant Antibody (TAB-623CL) (TAB-623CL)
- Species Reactivity: Human
- Type: Bovine IgG
- Application: Neut
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Anti-TNFα Recombinant Antibody (TAB-718) (TAB-718)
- Derivation: Mouse
- Species Reactivity: Human
- Type: F(ab')2 - G3 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
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Anti-Human TNF Recombinant Antibody Fab Fragment (MAK195) (TAB-132CQ-F(E))
- Species Reactivity: Human
- Application: ELISA, Neut
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Anti-Human TNF Single Domain Antibody (TAB-412CQ), Research Grade Biosimilar (TAB-412CQ)
- Species Reactivity: Human, Mouse
- Type: Single domain antibody
- Application: ELISA, Inhib
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Rabbit Anti-TNF Recombinant Antibody; scFv Fragment (TAB-271CQ-S(P)) (TAB-271CQ-S(P))
- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, WB
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Anti-Human TNF Recombinant Antibody (TAB-117CQ) (TAB-117CQ)
- Species Reactivity: Human
- Application: ELISA, WB
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Anti-Human TNF Recombinant Antibody (A10G10) (TAB-112CQ)
- Species Reactivity: Human
- Application: Neut, ELISA, WB
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Anti-Human TNF Recombinant Antibody (Vh5/Vk12) (TAB-116CQ)
- Species Reactivity: Human
- Application: ELISA
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Rabbit Anti-TNF Recombinant Antibody (TAB-271CQ) (TAB-271CQ)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, Neut
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Anti-Human TNFα/RANKL Recombinant Antibody (8G12) (TAB-311CT)
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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Mouse Anti-IL17 Recombinant Antibody; Fab Fragment (TAB-028ZJ-F(E)) (TAB-028ZJ-F(E))
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Anti-Human IL-17 Recombinant Antibody Fab Fragment (TAB-029ZJ-F(E)) (TAB-029ZJ-F(E))
- Species Reactivity: Human
- Application: ELISA
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Mouse Anti-IL17 Recombinant Antibody; Fab Fragment (TAB-031ZJ-F(E)) (TAB-031ZJ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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Anti-Human TNFα/RANKL Recombinant Antibody scFv Fragment (8G12) (TAB-311CT-S(P))
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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Anti-Human TNFα/RANKL Recombinant Antibody Fab Fragment (8G12) (TAB-311CT-F(E))
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
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Recombinant Anti-IL17 × Anti-TNF Bispecific Antibody (CrossMab) (CROSS-L017)
- Targets: IL17 & TNF
- Type: CrossMab
- Application: FuncS, Promising therapeutic agent
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For Research Use Only. Not For Clinical Use.

Background

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

Related Diseases

Asthma

Inflammatory Bowel Diseases

Rheumatoid Arthritis

Related Signaling Pathways

TNF Signaling Pathway