IL17 & TNF
Enables tumor necrosis factor receptor binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of macromolecule metabolic process; and positive regulation of neuron death. Located in several cellular components, including external side of plasma membrane; extracellular space; and neuronal cell body. Used to study several diseases, including cerebrovascular disease (multiple); liver disease (multiple); peptic esophagitis; perinatal necrotizing enterocolitis; and periventricular leukomalacia. Biomarker of several diseases, including brain disease (multiple); congestive heart failure (multiple); inflammatory bowel disease (multiple); lung disease (multiple); and non-alcoholic fatty liver disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor).
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
-
- Targets: IL17 & TNF
- Type: CrossMab
- Application: FuncS, Promising therapeutic agent
Compare
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, FuncS
Compare
-
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
Compare
-
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
Compare
-
- Scaffold Name: Kunitz domains
- Target: TNFα
- Species Reactivity: Human
- Derivation: Phage display
Compare
-
- Scaffold Name: Z-domain of protein A
- Target: TNFα
- Species Reactivity: Human
- Derivation: Phage display
Compare
-
- Scaffold Name: Ubiquitin
- Target: TNFα
- Derivation: Phage display
Compare
-
- Scaffold Name: 10-FnIII
- Target: TNFα
- Species Reactivity: Human
- Derivation: mRNA Display
Compare
-
- Derivation: Cow
- Species Reactivity: Human
- Type: ADCC enhanced antibody
Compare
-
- Derivation: Human
- Species Reactivity: Human
- Type: [V-kappa]2 - Fc
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Compare
-
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab'
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
Compare
-
- Species Reactivity: Human
- Type: Bovine IgG
- Application: Neut
Compare
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Compare
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: F(ab')2 - G3 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Compare
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Compare
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG1, κ
- Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Compare
-
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, IHC, FC, FuncS
Compare
-
- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, WB
Compare
-
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Rabbit scFv
- Application: ELISA, FC, IF
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: FuncS
Compare
-
- Species Reactivity: Human, Mouse, Monkey
- Type: Humanized antibody
- Application: FuncS, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, IF
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human, Cynomolgous monkey
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human, Cynomolgous macaque
- Type: Human scFv
- Application: ELISA, FC, IF
Compare
-
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FuncS
Compare
-
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, IHC
Compare
-
- Species Reactivity: Human, Rabbit
- Type: Human scFv
- Application: ELISA, Block
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA
Compare
-
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human antibody
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC, Neut, WB
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
Compare
-
- Species Reactivity: Human, Cynomolgus monkey
- Type: Humanized antibody
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC, Neut, WB
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, BL
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Humanized antibody
- Application: FC, ELISA
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: WB
Compare
-
- Species Reactivity: Human
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Application: ELISA, WB
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Application: ELISA, FC, Neut
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Neut
Compare
-
- Derivation: Humanized
- Species Reactivity: Human, Rhesus macaque, Cynomolgus, Canine
- Type: Humanized antibody
- Application: ELISA, FC, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, Neut
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: FC, Neut
Compare
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC, Inhib
Compare
-
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human, Rhesus macaque, Mouse, Chimpanzee
- Type: Humanized scFv
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC, IF
Compare
-
- Species Reactivity: Human
- Application: Neut, ELISA, WB
Compare
-
- Species Reactivity: Cynomolgus monkey, Marmoset monkey, Human
- Type: Humanized antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, IF
Compare
-
- Species Reactivity: Human, Mouse, Chimpanze
- Type: Human antibody
- Application: ELISA, WB
Compare
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, Neut
Compare
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare
-
- Species Reactivity: Human, Cynomolgous macaque
- Type: Human IgG
- Application: ELISA, Inhib, Neut
Compare
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Application: ELISA
Compare
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
Compare
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
Compare
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
Compare
-
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Cynomolgus monkey, Canine, Human
- Type: Human antibody
- Application: ELISA, WB, Inhib, Neut
Compare
-
- Derivation: Mouse hybridoma cell line
- Species Reactivity: Human RANKL, Human THFα
- Application: Neut, ELISA, FC
Compare
-
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
Compare
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
Compare
-
- Species Reactivity: Cynomolgus monkey, Canine, Human
- Type: Human antibody
- Application: ELISA, WB, Inhib, Neut
Compare
-
- Species Reactivity: Human
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Application: ELISA
Compare
-
- Species Reactivity: Cynomolgus monkey, Marmoset monkey, Human
- Type: Humanized antibody
- Application: ELISA
Compare
-
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare
-
- Species Reactivity: Cynomolgus monkey, Canine, Human
- Type: Human antibody
- Application: ELISA, WB, Inhib, Neut
Compare
-
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
Compare
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare
-
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare
-
- Species Reactivity: Cynomolgus monkey, Marmoset monkey, Human
- Type: Humanized antibody
- Application: ELISA
Compare
-
- Derivation: HC & LC phage library
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
Compare
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.