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Integrin α4β7

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Anti-Integrin α4β7 Products

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For Research Use Only. Not For Clinical Use.


Background

Alpha4beta7 (α4β7) integrin is a protein receptor on lymphocytes and other leukocytes that binds to MAdCAM-1, a molecule on endothelial cells, directing immune cells to gut-associated lymphoid tissues, a process known as homing. It plays a critical role in controlling inflammation in the gut, and its dysfunction is linked to inflammatory bowel diseases (IBD).
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