Plasma proteins
Intracellular
Group enriched (Cardiomyocytes, Endothelial cells, Sertoli cells, Adipocytes, Smooth muscle cells)
Not detected in immune cells
Cell line enhanced (AF22, HUVEC TERT2, LHCN-M2, RH-30, SuSa, WM-115)
Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3 (By similarity).
Developmental protein
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For Research Use Only. Not For Clinical Use.