Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Intracellular
Low cell type specificity
Low immune cell specificity
Cell line enhanced (ASC diff)
Interacts with ABHD5; this association stimulates PNPLA2 triglyceride hydrolase activity (By similarity). Interacts with SERPINF1; this interaction stimulates the phospholipase A2 activity of PNPLA2 (PubMed:17032652). Despite a colocalization in lipid droplets, it probably does not interact with PLIN (By similarity). Interacts with PLIN5; prevents interaction with ABHD5 (By similarity). Interacts with FAF2 (PubMed:23297223).
Hydrolase
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For Research Use Only. Not For Clinical Use.