RAS
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, ICC/IF
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- Species Reactivity: human
- Type: scFv-Tat
- Application: FC, IF, FuncS
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- Species Reactivity: human
- Type: scFv-(+36GFP)
- Application: IF, ELISA, FuncS
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- Species Reactivity: human
- Type: scFv-(D-Arg)9
- Application: WB, CO-IP, FuncS
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For Research Use Only. Not For Clinical Use.