Enzymes, Metabolic proteins
Intracellular
Cell type enhanced (Hofbauer cells)
Low immune cell specificity
Cell line enhanced (BEWO)
Interacts with HK2; the interaction increases hexokinase HK2 activity in a hypoxia- and HIF1A-dependent manner, resulting in the regulation of mitochondrial membrane potential, thus increasing NADPH production and decreasing intracellular ROS levels (PubMed:23185017).
Hydrolase
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For Research Use Only. Not For Clinical Use.