TNFRSF13C
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell surviva
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P, ICC, IF
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Human scFv
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, IHC-P
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Human IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ICC, FC, WB, FUNC
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: FC, FuncS
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- Species Reactivity: Mouse
- Type: Rat IgG2b
- Application: FC, FuncS
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- Species Reactivity: Human, Cynomolgus
- Type: Human IgG2
- Application: ELISA, FC, Neut
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human, Cynomolgus
- Type: Human scFv
- Application: ELISA, FC, Neut
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human, Cynomolgus
- Type: Human Fab
- Application: ELISA, FC, Neut
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Human IgG
- Application: FuncS
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Block, FuncS
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For Research Use Only. Not For Clinical Use.