Anti-Human CD51 Recombinant Antibody (Intetumumab) (CAT#: TAB-076)
Recombinant monoclonal antibody to Integrin CD51. Intetumumab is a human monoclonal antibody used in the treatment of solid tumors.
Specific Inquiry
IHC
Figure 1 Immunohistochemical analysis of apoptosis, vessel density, and oxygenation in FaDu xenograft tumors.
Digital photographs were taken at ×40 magnification with a Leica microscope equipped with a digital camera. Right, quantification of apoptosis, CD31, and EF5 staining. Four fields per section per tumor were analyzed. Columns, mean of three tumors for each group; bars, SD.
Ning, S., Tian, J., Marshall, D. J., & Knox, S. J. (2010). Anti–αv Integrin Monoclonal Antibody Intetumumab Enhances the Efficacy of Radiation Therapy and Reduces Metastasis of Human Cancer Xenografts in Nude Rats. Cancer research, 70(19), 7591-7599.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut, ICC, IHC
- CAS
- 725735-28-4
- Generic Name
- Intetumumab
- UNII
- GQE1BJE2NI
- MW
- 145.6 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The ITGAV antibody has been reported in applications of ELISA, FC, IP, FuncS, IF, Neut, ICC, IHC.
Target
- Alternative Names
- Intetumumab;725735-28-4;CNTO 95;ITGAV;integrin, alpha V;antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR;integrin alpha-V;CD51;integrin alphaVbeta3;
- Gene ID
- 3685
- UniProt ID
- P06756
Related Resources
Please refer to Intetumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Intetumumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Intetumumab"
Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Intetumumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Integrin CD51. Intetumumab is a human monoclonal antibody used in the treatment of solid tumors.
See other products for "ITGAV"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H01 | Anti-Human ITGAV Recombinant Antibody (Abituzumab) | Inhib, Agonist | IgG2 - kappa |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-250 | Mouse Anti-ITGAV Recombinant Antibody (clone 17E6); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| HPAB-1767-FY-F(E) | Human Anti-ITGAV Recombinant Antibody (clone 12G3); scFv Fragment | Cyt, ELISA | Humanized scFv |
| HPAB-1768-FY-F(E) | Human Anti-ITGAV Recombinant Antibody (clone 3F2); scFv Fragment | Cyt, ELISA | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-250 | Mouse Anti-ITGAV Recombinant Antibody (clone 17E6); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
| HPAB-1767-FY-S(P) | Human Anti-ITGAV Recombinant Antibody (clone 12G3); Fab Fragment | Cyt, ELISA | Humanized Fab |
| HPAB-1768-FY-S(P) | Human Anti-ITGAV Recombinant Antibody (clone 3F2); Fab Fragment | Cyt, ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-191-S (P) | Recombinant Mouse Anti-αVβ3 Ectodomain Antibody scFv Fragment (17E6) | Neut, FuncS | scFv |
| PABX-191-F (E) | Recombinant Mouse Anti-αVβ3 Ectodomain Antibody Fab Fragment (17E6) | Neut, FuncS | Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1537CQ | Recombinant Mouse Anti-ITGAV Antibody (272-17E6) | Inhib, ICC/IF, BL, FC, ELISA, IP | IgG1 |
| NEUT-1577CQ | Recombinant Mouse Anti-ITGAV Antibody (13C2) | FC, IHC-Fr, ICC, IP, ELISA, Depletion, BL, Adhesion | IgG1, κ |
| NEUT-1578CQ | Recombinant Mouse Anti-ITGAV Antibody (NKI-M9) | FC, IF, ELISA, BL, IP | IgG2a, κ |
| NEUT-1580CQ | Recombinant Mouse Anti-ITGAV Antibody (27.1) | ICC/IF, FC, IP, IHC-Fr, BL | IgG1 |
| NEUT-1581CQ | Recombinant Mouse Anti-ITGAV Antibody (P5H9) | CyTOF, BL, FC, IP, ICC | IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1582CQ | Recombinant Rat Anti-Itgav Antibody (RMV-7) | FC, FuncS, IP, Neut | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1880 | Hi-Affi™ Recombinant Rabbit Anti-ITGAV Monoclonal Antibody (DS1880AB) | WB, FC | IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-076 | Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Intetumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H01 | Afuco™ Anti-ITGAV ADCC Recombinant Antibody (Abituzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1187CQ | Mouse Anti-ITGAV Recombinant Antibody (clone EM01309) | WB, ELISA, FC, IHC | Mouse IgG1 |
| PABS-0202 | Mouse Anti-ITGAV Recombinant Antibody (clone 8B8) | ELISA | Mouse IgG |
| PABS-0203 | Mouse Anti-ITGAV Recombinant Antibody (clone 68) | ELISA | Mouse IgG |
| ZG-1065F | Mouse Anti-ITGAV Recombinant Antibody (clone NKI-M7 (former AMF7)) | ELISA, FC, IHC-Fr, IP | Mouse IgG1 |
| VS3-FY773 | Recombinant Rabbit Anti-ITGAV Antibody (clone R02-6G3) | WB, ICC, IF, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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