What is the nature of this PCSK9 antibody?

This is a Recombinant Humanized Antibody (from mouse) that targets Human PCSK9. It is an IgG2, kappa isotype produced in CHO cells. It has been validated for a wide range of applications including Neutralization, ELISA, IF, IP, and Flow Cytometry.

What is the purity of this antibody?

This antibody has a high purity of greater than 95.0% as determined by SDS-PAGE. It is supplied unconjugated and preservative-free, making it suitable for functional studies (FuncS) and other sensitive immunological methods.

Anti-Human PCSK9 Recombinant Antibody (TAB-H59)

CAT#: TAB-H59

Recombinant Humanized (from mouse) antibody to Human PCSK9

Gene Expression

RNA Expression Figure 1 RNA cell line category: Cell line enhanced (A-431, CACO-2, HaCaT, HeLa, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169174-PCSK9

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Specifications

Host Species
Mouse

Derivation
Humanized (from mouse)

Type
IgG2 - kappa

Specificity
PCSK9(proprotein convertase subtilisin/kexin type 9, neural apoptosis-regulated convertase 1, NARC1, NARC-1, proproteine convertase 9, PC9) [Homo sapiens]

Species Reactivity
Human

Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.

MW
145.3 kDa

Related Disease
Hypercholesterolemia

Product Property

Purity
>95.0% as determined by analysis by SDS-PAGE.

Target

Alternative Names
Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9; NARC-1; NARC1; PC9; Convertase Subtilisin/Kexin Type 9 Preproprotein; Hypercholesterolemia, Autosomal Dominant 3; Neural Apoptosis Regulated Convertase 1; Neural Apoptosis-Regulated Convertase 1

Gene ID
353175

UniProt ID
Q8NBP7

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Breast cancer biomarkers at key points during disease progression

Robust PCSK9 Antibody

This Anti-Human PCSK9 Recombinant Antibody (TAB-H59) is a workhorse. We used it for Western Blot, ELISA, and Immunofluorescence. It recognized the protein in all applications. The humanized IgG2, kappa format is very stable and specific.

Validated for Functional Assays

We also employed this antibody in neutralization assays (Neut) and functional studies. It effectively targeted PCSK9. The high purity (>95%) and preservative-free formulation make it ideal for these sensitive experiments. A top-tier reagent for cholesterol metabolism research.

Q&As

What is the nature of this PCSK9 antibody?

A: This is a Recombinant Humanized Antibody (from mouse) that targets Human PCSK9. It is an IgG2, kappa isotype produced in CHO cells. It has been validated for a wide range of applications including Neutralization, ELISA, IF, IP, and Flow Cytometry.
What is the purity of this antibody?

A: This antibody has a high purity of greater than 95.0% as determined by SDS-PAGE. It is supplied unconjugated and preservative-free, making it suitable for functional studies (FuncS) and other sensitive immunological methods.

View the frequently asked questions answered by Creative Biolabs Support.

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Biosimilar Overview

Please refer to Ralpancizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ralpancizumab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-H59.pdf

MSDS

MSDS - TAB-H59.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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