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Bevacizumab (TP-078CL)

A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Cancer
Therapeutic
Bevacizumab
Trade Name
Bevacizumab
Function
Humanized mAb that binds all isoforms of veGFA
Examples of Clinical Use
Colorectal cancer, non-small-cell lung cancer
References
Synonyms
antiVEGF, bevacizumab

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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