Anti-Human C5 Recombinant Antibody (Pexelizumab) (CAT#: TAB-901)
Recombinant humanized (from mouse) antibody expressed in CHO binding to human Complement component 5. Pexelizumab is a drug designed to reduce side effects of coronary artery bypass grafting and angioplasty, among other types of cardiac surgery. It is a single chain variable fragment of a monoclonal antibody targeted against component 5 of the complement system.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (A549, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000106804-C5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000106804-C5
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- scFv
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP, ICC
- Generic Name
- Pexelizumab
- ChEMBL
- CHZ6OLQ3UU
- Related Disease
- Cardiopulmonary bypass (CPB)
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Applications
- Application Notes
- The C5 antibody has been reported in applications of PD, CK-MB, Inhib.
Target
- Alternative Names
- Pexelizumab;h5G1.1-scFv;C5;complement component 5;complement C5;CPAMD4;anaphylatoxin C5a analog;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4;FLJ17816;FLJ17822;MGC142298;
- Gene ID
- 727
- UniProt ID
- P01031
Related Resources
Systemic Lupus Erythematosus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Pexelizumab"
DrugMonitor™ Anti-Pexelizumab Antibody (VS-1224-YC922)Pexelizumab is a humanized monoclonal antibody with immunosuppressive properties, currently being investigated by Alexion Pharmaceuticals. The DrugMonitor™ Anti-Pexelizumab Antibody (VS-1224-YC922) is an anti-drug antibody (ADA) against Pexelizumab. This drug-based antibody is raised in mice immunized with the Pexelizumab. The anti-Pexelizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Pexelizumab in samples.
See other products for "C5"
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-028 | Human Anti-C5 Recombinant Antibody Fab Fragment (PFBL-028) | Neut, FuncS | Human Fab |
| HPAB-0652LY-F(E) | Mouse Anti-C5 Recombinant Antibody; Fab Fragment (HPAB-0652LY-F(E)) | IP, RIA, ELISA, WB | Mouse Fab |
| PFBC-462 | Human Anti-C5 Recombinant Antibody Fab Fragment (PFBC-462) | ELISA, WB, FC, Neut | Human Fab |
| HPAB-1484-FY-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-1484-FY-S(P)) | ELISA, Neut | Mouse scFv |
| HPAB-1485-FY-S(P) | Mouse Anti-C5 Recombinant Antibody; scFv Fragment (HPAB-1485-FY-S(P)) | ELISA, Neut | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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