Pseudomonas aeruginosa possesses multiple mechanisms of antibiotic resistance, leading to high morbidity and mortality rates. It may result in complex infections and dangerous septic cases in critically ill patients. In a recentRead More…
Some HIV-1 carriers who received early antiretroviral therapy (ART) for several years can maintain long-term control over the virus after treatment interruption. However, the mechanism behind this post-treatment control is not fullyRead More…
Cellular secretions play various crucial roles within the body. However, methods to connect this functional information with surface markers and the transcriptome have been lacking. In a recent research paper published inRead More…
Immunotherapy has revolutionized the treatment of many cancer types. However, for reasons that remain poorly understood, not all patients respond equally from these potent therapies. In a recent study, researchers from HarvardRead More…
In a recently published study, researchers from the Max Planck Institute for Dynamics and Self-Organization in Germany, the University of Cologne, and the University of Washington found that a carefully designed mixtureRead More…
AstraZeneca recently announced that the European Commission (EC) has approved its long-acting antibody therapy Evusheld (tesaglizumab in combination with cilgravizumab, formerly AZD7442) for the treatment of adults and adolescents with severe COVID-19Read More…
Since the first therapeutic antibody Muromonab-CD3 was approved in 1986, more than 100 antibodies have been approved for marketing. Based on their properties, antibodies can be divided into four categories: mouse antibodies,Read More…
The path to finding a therapeutic antibody that leads to significant medical improvements is often complicated, long, and costly. Many criteria have to be taken into account in order to begin theRead More…
Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. According to a recent study published in the international journalRead More…
A mix of two monoclonal antibodies against HIV tamped down virus levels in patients not taking antiretroviral medication, according to the results of two early-stage clinical trials reported in nature. After several infusionsRead More…