Some HIV-1 carriers who received early antiretroviral therapy (ART) for several years can maintain long-term control over the virus after treatment interruption. However, the mechanism behind this post-treatment control is not fullyRead More…
Immunotherapy has revolutionized the treatment of many cancer types. However, for reasons that remain poorly understood, not all patients respond equally from these potent therapies. In a recent study, researchers from HarvardRead More…
The morbidity and mortality of intestinal tumors are among the top malignant tumors, and they are major diseases that seriously threaten people’s health. The prognosis for some patients with gastrointestinal malignancies hasRead More…
Neoantigens are peptides derived from nonsynonymous mutations in human leukocyte antigens (HLAs) that are recognized by antitumor T cells. The large diversity of HLA alleles and limited clinical samples often narrow scientists’Read More…
Many cancer cells never leave their original tumor tissue. Some cancer cells have evolved the ability to migrate to other tissues, but they will become dormant once they are unable to formRead More…
The paradigm of the adenoma-cancer sequence has typically focused on cancer cells in colorectal cancer (CRC) development that is already validated to entail heterologous interactions between altered cells and their surrounding microenvironment.Read More…
Astellas recently announced positive top-line results of the Phase III SPOTLIGHT clinical trial designed to evaluate the efficacy and safety of zolbetuximab in combination with mFOLFOX6—a combination regimen including oxaliplatin, calcium folinate,Read More…
As multispecifics is hailed the fourth wave of drug discovery, with more clinical candidates and commercial success than ever before, the 13th World Bispecific Summit arrived at a pivotal time to deliver the holyRead More…
The latest update— Cases of COVID-19 in the U.S. at a Glance on April 3, 2020, which include both confirmed and presumptive positive cases of COVID-19 reported to CDC or tested atRead More…
According to a study recently published in Cancer Research by researchers and colleagues at the Belvich Institute of Biomedicine at the University of Barcelona, a large number of replicated chromosome regions areRead More…