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PSCA

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For Research Use Only. Not For Clinical Use.


Background

PSCA is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein that is overexpressed in prostate cancer and other malignancies. It is being investigated as a potential target for cancer immunotherapy.
Protein class

Cancer-related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enriched (Gastric mucus-secreting cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CAPAN-2, HeLa, OE19, RT4)

Interaction

Interacts with CHRNA4.

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