APC-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer (CAT#: MHC-LC672)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of IAPP-derived peptide of KLQVFLIVL sequence covering 5-13 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
Figure 2 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
Figure 3 Low expression in colon
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
Figure 4 Pancreas
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- IAPP
- Antigen Species
- Human
- Peptide
- KLQVFLIVL
- Range
- 5-13
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.
- Alternative Names
- IAPP; islet amyloid polypeptide; DAP; IAP
- Gene ID
- 3375
- UniProt ID
- P10997
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IAPP"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2254z | Mouse Anti-IAPP Recombinant Antibody (clone 35D9) | ICC, IF, IHC | Mouse IgG1 |
| HPAB-0295-YC | Human Anti-IAPP Recombinant Antibody (clone HlLl) | FuncS | Humanized IgG1, κ |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-375CL | Human Anti-IAPP Recombinant Antibody (TAB-375CL) | ELISA | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-118CT-S(P)) | ELISA | Human scFv |
| TAB-119CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-119CT-S(P)) | ELISA | Human scFv |
| TAB-120CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-120CT-S(P)) | ELISA | Human scFv |
| TAB-118CT-F(E) | Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-118CT-F(E)) | ELISA | Human Fab |
| TAB-119CT-F(E) | Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-119CT-F(E)) | ELISA | Human Fab |
MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC671 | PE-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC673 | BV421-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-YF299 | A*02:01/Human IAPP (KLQVFLIVL) MHC Monomer | MHC Multimer |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-S(P) | Human Anti-IAPP Recombinant Antibody (clone HlLl); scFv Fragment | FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-F(E) | Human Anti-IAPP Recombinant Antibody (clone HlLl); Fab Fragment | FuncS | Humanized Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MHC-LC672. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.