APC-A*03:01/Human PLP1 (KLIETYFSK) MHC Tetramer (CAT#: MHC-LC1611)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PLP1-derived peptide of KLIETYFSK covering 45-53 and A*03:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
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Specifications

  • Allele
  • A*03:01
  • Class
  • Class I
  • Antigen
  • PLP1
  • Antigen Species
  • Human
  • Peptide
  • KLIETYFSK
  • Range
  • 45-53
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.
  • Alternative Names
  • PLP1; proteolipid protein 1; PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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