APC-B*07:02/Human POLR2A (TPQSNRPVM) MHC Tetramer (CAT#: MHC-LC2085)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human POLR2A of peptide TPQSNRPVM covering 527-535 and B*07:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • B*07:02
  • Class
  • Class I
  • Antigen
  • POLR2A
  • Antigen Species
  • Human
  • Peptide
  • TPQSNRPVM
  • Range
  • 527-535
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • POLR2A; DNA-directed RNA polymerase II subunit RPB1; RPB1; RPO2; POLR2; POLRA; RPBh1; RPOL2; RpIILS; hsRPB1; hRPB220

Downloads

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CAT Product Name Application Type
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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