Products

CBGlyco™ Alkoxyamine-PEG12-Biotin (Glyco-022CL)

Alkoxyamine-PEG12-Biotin is a biotinylation reagent containing a long, 12-unit polyethylene glycol (PEG) spacer for biotinylating macromolecules at carbohydrate groups that have been oxidized to form aldehydes.      

Specifications
Product Size
50 mg
Label or Dye
Biotin
Spacer
Pegylated, Extra-Long
Solubility
DMSO (Dimethylsulfoxide), DMF (Dimethylformamide), Water
Cell Permeability
Cell-Impermeant
Chemical Reactivity
Aldehyde, Ketone
Contents & storage
Store at -20°C. Shipped at ambient temperature.
BACKGROUND
Description
Aminooxy-biotin reagents such as this one are useful for biotinylating glycoproteins and other molecules that have oxidizable polysaccharides groups. The alkoxyamine group (also called an aminooxy or aminoxy group) conjugates to aldehydes of oxidized sugars. Alkoxyamine-PEG-Biotin reagents contain a multi-functional extended spacer arm that is a flexible, non-immunogenic hydrophilic polyethylene glycol (PEG), which imparts water solubility to labeled molecules. Consequently, antibodies labeled with pegylated biotin reagents exhibit less aggregation when stored in solution compared to antibodies labeled with reagents having only hydrocarbon spacers.
Properties

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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