Anti-Human CEA Recombinant Antibody Fab Fragment (Arcitumomab) (CAT#: TAB-014-F(E))

Recombinant monoclonal antibody Fragment Fab to Human CEA. Technetium (99mTc) arcitumomab is a drug used for the diagnostic imaging of colorectal cancers. It consists of the Fab' fragment of a monoclonal antibody (arcitumomab, trade name CEA-Scan) and a radionuclide, technetium-99m. Technetium (99mTc) arcitumomab is an immunoconjugate. Arcitumomab is a Fab' fragment of IMMU-4, a murine IgG1 monoclonal antibody extracted from the ascites of mice. The enzyme pepsin cleaves the F(ab')2 fragment off the antibody. From this, the Fab' fragment is prepared by mild reduction. Before application, arcitumomab is reconstituted with a solution of the radioactive agent sodium pertechnetate (99mTc) from a technetium generator.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Full length native protein (CEA)
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Fab' - G1
  • Specificity
  • Tested positive against native human antigen
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • Trade name
  • Technetium (99mTc) arcitumomab
  • CAS
  • 154361-48-5
  • Generic Name
  • Arcitumomab
  • Biological Half-Life
  • 13 ± 4 hours
  • ATC Code
  • V09IA06
  • UNII
  • 029JF1SCU8
  • MW
  • 50 kDa
  • Related Disease
  • Colorectal cancers (radiodiagnostic imaging of tumors)

Product Property

  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

Target

  • Alternative Names
  • Arcitumomab;Technetium (99mTc) arcitumomab;154361-48-5;IMMU-4;NP-4;CEACAM1;carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein);BGP;carcinoembryonic antigen-related cell adhesion molecule 1;BGP1;CD66a;antigen CD66;CD66a antigen

Related Resources

  • Biosimilar Overview
Please refer to Arcitumomab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Arcitumomab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CEACAM1"

Humanized Antibody

CAT Product Name Application Type
TAB-156CL Human Anti-CEACAM1 Recombinant Antibody (TAB-156CL) ELISA Human IgG

Chimeric Antibody

CAT Product Name Application Type
TAB-443LC Human Anti-CEACAM1 Recombinant Antibody (TAB-443LC) Block, Cyt, ELISA, FC, FuncS Chimeric (Mouse/Human) IgG1, κ
TAB-443LC-S(P) Mouse Anti-CEACAM1 Recombinant Antibody; scFv Fragment (TAB-443LC-S(P)) FC, SPR, IHC, ELISA Mouse scFv
TAB-443LC-F(E) Human Anti-CEACAM1 Recombinant Antibody; Fab Fragment (TAB-443LC-F(E)) FC, SPR, IHC, ELISA Chimeric (Mouse/Human) Fab

Blocking Antibody

CAT Product Name Application Type
NEUT-453CQ Mouse Anti-Ceacam1 Recombinant Antibody (clone MAb-CC1) FC, WB, IP, IHC, ELISA, Block Mouse IgG1, κ

Neutralizing Antibody

CAT Product Name Application Type
NEUT-454CQ Mouse Anti-Ceacam1 Recombinant Antibody (clone CC1) WB, Neut, FC, FuncS, IHC, IHC-Fr, IHC-P, IP Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0648 Hi-Affi™ Rabbit Anti-CEACAM1 Recombinant Antibody (clone DS648AB) IHC-P, WB Rabbit IgG

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0572CQ Rat Anti-CEACAM1 Recombinant Antibody (clone YTH71.3) ELISA Rat IgG2a

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for TAB-014-F(E). Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare