Anti-Human ERBB3/ErbB 3 Recombinant Antibody (Seribantumab) (CAT#: TAB-892)

Recombinant humanized antibody expressed in CHO binding to human ERBB3. Seribantumab is used to treat cancer.


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ELISA

Figure 1 Anti-ERBB3 Recombinant Antibody (TAB-892) in ELISA

Figure 1 Anti-ERBB3 Recombinant Antibody (TAB-892) in ELISA

ELISA analysis of TAB-892 was performed by coating with human ERBB3 protein (2 µg/mL). Then blocked with BSA and incubated with TAB-892. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 5000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.

WB

Figure 2 Anti-ERBB3 Recombinant Antibody (TAB-892) in WB

Figure 2 Anti-ERBB3 Recombinant Antibody (TAB-892) in WB

Western blot analysis of TAB-892 was performed with human ERBB3 protein in reduced condition Lane 1, Lane 2 and Lane 3 (0.1 μg, 0.3 μg and 0.6 μg, respectively) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-892 (2 μg/mL) and HRP-conjugated goat anti-human IgG as a secondary antibody (1: 6000). Chemiluminescent detection was performed.

DB

Figure 3 Anti-ERBB3 Recombinant Antibody (TAB-892) in DB

Figure 3 Anti-ERBB3 Recombinant Antibody (TAB-892) in DB

Dot Blot analysis of TAB-892 was performed by coating with human ERBB3 protein.

TAB-892 incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-human IgG as a secondary antibody (1: 6000)
NC: Negative Control PC: Positive Control


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • undefined
  • Derivation
  • Humanized
  • Type
  • IgG2 - lambda
  • Species Reactivity
  • Human
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC, ICC
  • CAS
  • 1334296-12-6
  • Generic Name
  • Seribantumab
  • MW
  • 143.2 kDa
  • Related Disease
  • Breast cancers

Product Property

  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • The ERBB3 antibody has been reported in applications of Inhib, Activ, WB.

Target

  • Alternative Names
  • Seribantumab;1334296-12-6;MM-121;SAR256212;ERBB3;v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian);LCCS2, lethal congenital contracture syndrome 2;receptor tyrosine-protein kinase erbB-3;HER3;proto-oncogene-like protein c-ErbB-3;tyrosine k

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Seribantumab"

Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized antibody expressed in CHO binding to human ERBB3. Seribantumab is used to treat cancer.

See other products for "ERBB3"

Immunotoxin

CAT Product Name Application Type
AGTO-L074E HRGβ2-PE immunotoxin Cytotoxicity assay, Functional assay

Humanized Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-061CT Human Anti-ERBB3 Recombinant Antibody (TAB-061CT) Inhib, ELISA Chimeric (Rabbit/Human) antibody
TAB-061CT-S(P) Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P)) Inhib, ELISA Human scFv
TAB-061CT-F(E) Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E)) Inhib, ELISA Chimeric (Rabbit/Human) Fab

Mouse Antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1179 Hi-Affi™ Rabbit Anti-ERBB3 Recombinant Antibody (clone DS1179AB) ICC, IF, WB Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H21 Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-422CQ Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Elgemtumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, BL ADCC enhanced antibody
AFC-TAB-189 Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced IP, IF, FuncS, FC, Neut, ELISA Human IgG1, κ
AFC-TAB-H22 Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotuzumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-892 Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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