Products

Anti-AR × Anti-DNA Bispecific Antibody (TAND-L031)

Recombinant Anti-AR × Anti-DNA Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. TandAbs do not carry Fc domains, are smaller than whole IgGs or IgG-derived bsAbs, but larger than BiTEs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with BiTEs. It was designed for the treatment of allergic asthma and dermatitis.      

Specifications
Targets
AR & DNA
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
AR
Host
Mouse
Target 2
DNA
Host
Mouse
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Allergic asthma and Dermatitis.
Targets
Target 1
AR
Gene ID
367
UniProt ID
P10275
Alternative Names
AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1
Target 2
DNA

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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