Recombinant Anti-CEA × Anti-HSG Bispecific Antibody (Fab2) (CAT#: FAB-L073)
Recombinant Anti-CEA × Anti-HSG Bispecific Antibody (Fab2) is composed of the Fab of the anti-CEA monoclonal antibody and Fab of an antibody specific for HSG. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG, and therefore it clears from the blood naturally at a faster rate. The BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It was designed for the imaging and treatment of CEA-expressing tumors.
Specific Inquiry
Specifications
- Target
- CEA & HSG
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CEA
- Host Species 1
- Human
- Target 2
- HSG
- Host Species 2
- Human
- Application
- FuncS, Pretargeting system for radioimaging and radiotherapy
- Related Disease
- CEA-expressing tumors
Target
- Target 1
- CEA
- Gene ID
- 1048
- UniProt ID
- A0A024R0K5
- Alternative Names
- CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
- Target 2
- HSG
- Alternative Names
- histaminyl-succinyl-glycine; HSG
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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