Products

Anti-IL-17A × Anti-IL-23 Bispecific Antibody (TAND-L018)

Recombinant Anti-IL-17A × Anti-IL-23 Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. TandAbs do not carry Fc domains. So they are smaller than whole IgGs or IgG-derived BsAbs but larger than BiTEs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with BiTEs. This BsAb is capable of simultaneous blocking two cytokines and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of autoimmune disorders, cancer and neoplastic diseases.      

Specifications
Targets
IL-17A & IL-23
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
IL-17A
Host
Human
Target 2
IL-23
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Autoimmune disorders,Cancer/neoplastic diseases
Targets
Target 1
IL-17A
Gene ID
3605
UniProt ID
Q16552
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8
Target 2
IL-23
Gene ID
51561
UniProt ID
Q9NPF7
Alternative Names
P19; SGRF; IL-23; IL-23A; IL23P19

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2018 Creative-Biolabs All Rights Reserved