Products

Anti-MET × Anti-VEGF IgG-IgG (MV10A) (BSIG-MZ001)

This bispecific antibody shows significant synergistic suppression effects against HGF- and VEGF-dependent HUVEC cell proliferation. It is also capable of inhibiting the phosphorylation of AKT and suppressing tumor cell invasion as well.      

Specifications
Targets
MET & VEGF
Type
IgG-IgG
Expression Host
CHO
Species Reactivity
Human
Target 1
MET
Host
Human
Clone
L3-1Y
Target 2
VEGF
Host
Human
Clone
Bevacizumab
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
ELISA
Related Disease
Gastric cancer
Targets
Target 1
MET
Gene ID
4233
UniProt ID
A0A024R759
Alternative Names
MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor
Target 2
VEGF
Alternative Names
VEGF; Vascular endothelial growth factor

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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