Products

Anti-PDGFR2 × Anti-VEGFR2 Bispecific Antibody (TAND-L048)

Recombinant Anti-PDGFR2 × Anti-VEGFR2 Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. TandAbs do not carry Fc domains, are smaller than whole IgGs or IgG-derived bsAbs, but larger than BiTEs. Therefore, they have a shorter serum half-life than IgGs but remain longer in the circulation compared with BiTEs. This BsAb can block 2 receptors. It was designed for the treatment of various tumors.      

Specifications
Targets
PDGFR2 & VEGFR2
Type
TandAb
Expression Host
CHO
Species Reactivity
Mouse
Target 1
PDGFR2
Host
Human
Target 2
VEGFR2
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Various tumors
Targets
Target 1
PDGFR2
Gene ID
18595
UniProt ID
P26618
Alternative Names
PDGFRA; platelet derived growth factor receptor, alpha polypeptide; CD140a; Pdgfr-2; AI115593; platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGF-R-alpha
Target 2
VEGFR2
Gene ID
16542
UniProt ID
Q8VCD0
Alternative Names
KDR; kinase insert domain protein receptor; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; vascular endothelial growth factor receptor 2; kinase NYK; VEGF receptor-2; fetal liver kinase 1; protein-tyrosine kinase receptor flk-1; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; vascular endothelial growth factor receptor- 2; soluble vascular endothelial growth factor receptor 2

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2018 Creative-Biolabs All Rights Reserved