Products

Coagulation factor VIIa Recombinant Human (TP-051CL)

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.      

Specifications
Classify
Protein therapeutics augmenting an existing pathway: Haemostasis and thrombosis
Therapeutic
Factor VIIa
Trade Name
Novoseven
Function
Pro-thrombotic (activated factor vii; initiates the coagulation cascade)
Examples of Clinical Use
Haemorrhage in patients with haemophilia A or B and inhibitors to factor viii or factor iX
References
Synonyms
Coagulation factor VIIa, Coagulation factor VIIa (recombinant), Eptacog alfa, Eptacog alfa (activated), rFVIIa
UniProt
P08709
Genbank
M13232

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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