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Cystine knot anti-integrin (SCK-L069)

The Cystine knot that bound Integrin avb3 was isolated from the library using Phage display techonology. After affinity maturation, Cystine knot variants were identified having affinities for Integrin avb3 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
Cystine knot
Origin
Agouti-related protein (AgRP)
Core Structure
A double-stranded b sheet and four disulfide bond
Variable Regions
1–2 Loops
Target
Integrin avb3
Species Reactivity
Human
Expression Host
BL21 (DE3) cells
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
agouti-related protein (AgRP); Cystine knot; integrin

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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