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EETI-II anti-CELA1 (SEE-L086)

The EETI-II that bound Porcine pancreatic elastase (PPE) was isolated from the library using mRNA display techonology. After affinity maturation, EETI-II variants were identified having affinities (KD=24 pM) for Porcine pancreatic elastase (PPE) as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
EETI-II
Origin
Trypsin-specific squash inhibitor EETI II
Core Structure
Coiled, cys-rich (28)
Variable Regions
6 aa
Target
Porcine pancreatic elastase (PPE)
Species Reactivity
Porcine
Expression Host
E. coli
Affinity Constant
24 pM
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
trypsin-specific squash inhibitor EETI II; EETI-II; ELA1; ELS1; Elastase-1
Entrez Gene ID
396766
UniProt ID
P00772

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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