H-2Kd/L. monocytogenes LLO (GYKDGNEYI) MHC Tetramer (CAT#: MHC-LC762)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of L. monocytogenes-derived peptide of GYKDGNEYI sequence covering 91-99 and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • L. monocytogenes LLO
  • Antigen Species
  • L. monocytogenes
  • Peptide
  • GYKDGNEYI
  • Range
  • 91-99
  • Application
  • FCM

Target

  • Antigen Introduction
  • Listeria monocytogenes is the species of pathogenic bacteria that causes the infection listeriosis. It is a facultative anaerobic bacterium, capable of surviving in the presence or absence of oxygen. It can grow and reproduce inside the host's cells and is one of the most virulent foodborne pathogens, with 20 to 30% of food borne listeriosis infections in high-risk individuals may be fatal.Responsible for an estimated 1,600 illnesses and 260 deaths in the United States annually, listeriosis ranks third in total number of deaths among food borne bacterial pathogens, with fatality rates exceeding even Salmonella and Clostridium botulinum. In the European Union listeriosis follows an upward trend that began in 2008, causing 2,161 confirmed cases and 210 reported deaths in 2014, 16% more than in 2013. Listeriosis mortality rates are also in the EU higher than for other food-borne pathogens.
  • Alternative Names
  • L. monocytogenes LLO; Listeria monocytogenes listeriolysin O; hly

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MHC Tetramer for Bacteriology

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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